Our research

Bosi, Alessandro; Xu, Yunwen; Gasparini, Alessandro; Wettermark, Björn; Barany, Peter; Bellocco, Rino; Inker, Lesley A.; Chang, Alex R.; McAdams-DeMarco, Mara; Grams, Morgan E.; Shin, Jung-Im; Carrero, Juan J.

Use of nephrotoxic medications in adults with chronic kidney disease in Swedish and US routine care

Degerstedt, Oliver; Gråsjö, Johan; Norberg, Anton; Sjögren, Erik; Hansson, Per; Lennernäs, Hans

Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue

De Jager, Veronique; Gupte, Nikhil; Nunes, Silvia; Barnes, Grace L.; Van Wijk, Rob C; Mostert, Joni; Dorman, Susan E.; Abulfathi, Ahmed A.; Upton, Caryn M.; Faraj, Alan; Nuermberger, Eric L.; Lamichhane, Gyanu; Svensson, Elin; Simonsson, Ulrika S. H.; Diacon, Andreas H.; Dooley, Kelly E.

Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial

Wanselius, Marcus; Searle, Sean; Rodler, Agnes; Tenje, Maria; Abrahmsen-Alami, Susanna; Hansson, Per

Microfluidics platform for studies of peptide - polyelectrolyte interaction

Wegler, Christine; Wiśniewski, Jacek R; Robertsen, Ida; Christensen, Hege; Kristoffer Hertel, Jens; Hjelmesaeth, Jøran; Jansson-Löfmark, Rasmus; Åsberg, Anders; Andersson, Tommy B; Artursson, Per

Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity.

Dubbelboer, Ilse R; Barmpatsalou, Vicky; Rodler, Agnes; Karlsson, Eva; Nunes, Sandro Filipe; Holmberg, Johanna; Haggstrom, Jens; Bergström, Christel

Gastrointestinal mucus in dog: Physiological characteristics, composition, and structural properties

Hanzel, Jurij; Dreesen, Erwin; Vermeire, Severine; Lowenberg, Mark; Hoentjen, Frank; Bossuyt, Peter; Clasquin, Esme; Baert, Filip J.; D'Haens, Geert R.; Mathot, Ron

Pharmacokinetic-Pharmacodynamic Model of Vedolizumab for Targeting Endoscopic Remission in Patients With Crohn Disease: Posthoc Analysis of the LOVE-CD Study

Mockeliunas, Laurynas; Keutzer, Lina; Sturkenboom, Marieke G. G.; Bolhuis, Mathieu S.; Hulskotte, Lotte M. G.; Akkerman, Onno W.; Simonsson, Ulrika S. H.

Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis

Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Thalberg, Kyrre; Alderborn, Göran

Effect of pressure drop on the in vitro dispersion of adhesive mixtures of different blend states for inhalation

Grisic, Ana-Marija; Xiong, Wenyuan; Tanneau, Lénaïg; Jönsson, Siv; Friberg, Lena; Karlsson, Mats; Dai, Haiqing; Zheng, Jenny; Girard, Pascal; Khandelwal, Akash

Model-Based Characterization of the Bidirectional Interaction Between Pharmacokinetics and Tumor Growth Dynamics in Patients with Metastatic Merkel Cell Carcinoma Treated with Avelumab

Sasaki, Tomohiro; Svensson, Elin; Wang, Xiaofeng; Wang, Yanlin; Hafkin, Jeffrey; Karlsson, Mats; Mallikaarjun, Suresh

Population Pharmacokinetic and Concentration-QTc Analysis of Delamanid in Pediatric Participants with Multidrug-Resistant Tuberculosis

Koele, Simon E.; van Beek, Stijn W.; Maartens, Gary; Brust, James C. M.; Svensson, Elin

Optimized Loading Dose Strategies for Bedaquiline When Restarting Interrupted Drug-Resistant Tuberculosis Treatment

Wang, Tianyan; Sarwar, Martuza; Whitchurch, Jonathan B.; Collins, Hilary M.; Green, Tami; Semenas, Julius; Ali, Amjad; Roberts, Christopher J.; Morris, Ryan D.; Hubert, Madlen; Chen, Sa; El-Schich, Zahra; Wingren, Anette G.; Grundström, Thomas; Lundmark, Richard; Mongan, Nigel P.; Gunhaga, Lena; Heery, David M.; Persson, Jenny L.

PIP5K1 alpha is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer

Frenk, Sammy; Temkin, Elizabeth; Lurie-Weinberger, Mor N.; Keren-Paz, Alona; Rov, Reut; Rakovitsky, Nadya; Wullfhart, Liat; Nutman, Amir; Daikos, George L.; Skiada, Anna; Durante-Mangoni, Emanuele; Benattar, Yael Dishon; Bitterman, Roni; Yahav, Dafna; Daitch, Vered; Bernardo, Mariano; Iossa, Domenico; Zusman, Oren; Friberg, Lena; Mouton, Johan W.; Theuretzbacher, Ursula; Leibovici, Leonard; Geffen, Yuval; Gershon, Rina; Paul, Mical; Carmeli, Yehuda

Large-scale WGS of carbapenem-resistant Acinetobacter baumannii isolates reveals patterns of dissemination of ST clades associated with antibiotic resistance

Lauren, Ida; Havervall, Sebastian; Ng, Henry; Lord, Martin; Pettke, Aleksandra; Greilert-Norin, Nina; Gabrielsson, Lena; Chourlia, Aikaterini; Amoedo-Leite, Catarina; Josyula, Vijay S.; Eltahir, Mohamed; Kerzeli, Iliana Kyriaki; Falk, August J.; Hober, Jonathan; Christ, Wanda; Wiberg, Anna; Hedhammar, My; Tegel, Hanna; Burman, Joachim; Xu, Feifei; Pin, Elisa; Manberg, Anna; Klingstrom, Jonas; Christoffersson, Gustaf; Hober, Sophia; Nilsson, Peter; Phillipson, Mia; Donnes, Pierre; Lindsay, Robin; Thalin, Charlotte; Mangsbo, Sara

Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology

Peters, Karsten; Dahlgren, David; Egerszegi, Peter Pal; Lennernäs, Hans; Sjöblom, Markus

Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats

Tahsin, Md. Rafat; Tithi, Tanzia Islam; Mim, Sabiha Rahman; Haque, Ehfazul; Sultana, Arifa; Bahar, Nasiba Binte; Ahmed, Raju; Chowdhury, Jakir Ahmed; Chowdhury, Abu Asad; Kabir, Shaila; Aktar, Fahima; Uddin, Md. Sahab; Amran, Md. Shah

In Vivo and In Silico Assessment of Diabetes Ameliorating Potentiality and Safety Profile of Gynura procumbens Leaves

Yin, Anyue; van Hasselt, Johan G. C.; Guchelaar, Henk-Jan; Friberg, Lena; Moes, Dirk Jan A. R.

Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance

Backstrom, E.; Erngren, T.; Fihn, B-M; Sadiq, M. W.; Lindberg, W.; Fridén, Markus; Grime, K.

Possible Extraction of Drugs from Lung Tissue During Broncho-alveolar Lavage Suggest Uncertainty in the Procedure's Utility for Quantitative Assessment of Airway Drug Exposure

Hjalte, Johanna; Hossain, Md Shakhawath; Hugerth, Andreas; Sjogren, Helen; Wahlgren, Marie; Larsson, Per; Lundberg, Dan

Aggregation Behavior of Structurally Similar Therapeutic Peptides Investigated by H-1 NMR and All-Atom Molecular Dynamics Simulations

Saran, Chitra; Sundqvist, Louise; Ho, Henry; Niskanen, Jonna; Honkakoski, Paavo; Brouwer, Kim L. R.

Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors

Berg, Staffan; Karrberg, Lillevi; Suljovic, Denny; Seeliger, Frank; Soderberg, Magnus; Perez-Alcazar, Marta; Van Zuydam, Natalie; Abrahamsson, Bertil; Hugerth, Andreas M.; Davies, Nigel; Bergström, Christel

Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat

Holder, Brianna M.; Tolan, Shaina E.; Heinrich, Kaleb K.; Miller, Kaitlin C.; Hudson, Natalie; Nehra, Geetika; Pizzo, Michelle E.; Storck, Steffen E.; Elmquist, William F.; Engelhardt, Britta; Loryan, Irena; Toborek, Michal; Bauer, Bjoern; Hartz, Anika M. S.; Kim, Brandon J.

Brain barriers virtual: an interim solution or future opportunity?

Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra; Gustafsson, Robert; Wiita, Elisee; Borhade, Sanjay; Green, Alanna C.; Vallin, Karl S. A.; Sarno, Antonio; Svensson, Richard; Gokturk, Camilla; Pham, Therese; Jemth, Ann-Sofie; Loseva, Olga; Cookson, Victoria; Kiweler, Nicole; Sandberg, Lars; Rasti, Azita; Unterlass, Judith E.; Haraldsson, Martin; Andersson, Yasmin; Scaletti, Emma R.; Bengtsson, Christoffer; Paulin, Cynthia B. J.; Sanjiv, Kumar; Abdurakhmanov, Eldar; Pudelko, Linda; Kunz, Ben; Desroses, Matthieu; Iliev, Petar; Farnegardh, Katarina; Kramer, Andreas; Garg, Neeraj; Michel, Maurice; Haggblad, Sara; Jarvius, Malin; Kalderen, Christina; Jensen, Amanda Bogedahl; Almlof, Ingrid; Karsten, Stella; Zhang, Si Min; Haggblad, Maria; Eriksson, Anders; Liu, Jianping; Glinghammar, Bjorn; Nekhotiaeva, Natalia; Klingegard, Fredrik; Koolmeister, Tobias; Martens, Ulf; Llona-Minguez, Sabin; Moulson, Ruth; Nordström, Helena; Parrow, Vendela; Dahllund, Leif; Sjoberg, Birger; Vargas, Irene L.; Vo, Duy Duc; Wannberg, Johan; Knapp, Stefan; Krokan, Hans E.; Arvidsson, Per, I; Scobie, Martin; Meiser, Johannes; Stenmark, Pal; Berglund, Ulrika Warpman; Homan, Evert J.; Helleday, Thomas

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Danho, Rabi; Schildkraut, Jodie A.; Zweijpfenning, Sanne M. H.; Svensson, Elin; Pennings, Lian J.; Kuipers, Saskia; Wertheim, Heiman F. L.; Boeree, Martin J.; Hoefsloot, Wouter; van Ingen, Jakko

Mycobacterium Growth Indicator Tube Time-To-Positivity Can Serve As an Early Biomarker of Treatment Response in Mycobacterium avium Complex Pulmonary Disease

Kvitne, Kine Eide; Robertsen, Ida; Skovlund, Eva; Christensen, Hege; Krogstad, Veronica; Wegler, Christine; Angeles, Philip Carlo; Wollmann, Birgit Malene; Hole, Kristine; Johnson, Line Kristin; Sandbu, Rune; Artursson, Per; Karlsson, Cecilia; Andersson, Shalini; Andersson, Tommy B.; Hjelmesaeth, Jøran; Jansson-Löfmark, Rasmus; Åsberg, Anders

Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity: a non-randomized three-armed controlled trial

Eriksen, Jonas Borregaard; Jacobsen, Ann-Christin; Christensen, Katrine Taekker; Bauer-Brandl, Annette; Brandl, Martin

'Stirred not Shaken!' Comparing Agitation Methods for Permeability Studies Using a Novel Type of 96-Well Sandwich-Plates

Wang, Zhigang; Verstockt, Bram; Sabino, Joao; Vermeire, Severine; Ferrante, Marc; Declerck, Paul; Dreesen, Erwin

Population pharmacokinetic-pharmacodynamic model-based exploration of alternative ustekinumab dosage regimens for patients with Crohn's disease

Cano-Cebrian, Maria-Jose; Dahlgren, David; Kullenberg, Fredrik; Peters, Karsten; Olander, Tobias; Sjöblom, Markus; Lennernäs, Hans

Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats

Khaled, Jaafar; Kopsida, Maria; Lennernäs, Hans; Heindryckx, Femke

Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma

Al-Tikriti, Yassir; Hansson, Per

Drug-Induced Phase Separation in Polyelectrolyte Microgels

Palica, Katarzyna; Vorácová, Manuela; Skagseth, Susann; Andersson Rasmussen, Anna; Allander, Lisa; Hubert, Madlen; Sandegren, Linus; Schrøder Leiros, Hanna-Kirstirep; Andersson, Hanna; Erdélyi, Máté

Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters

Cantarero-Arevalo, Lourdes; Norgaard, Lotte S.; Kälvemark Sporrong, Sofia; Jacobsen, Ramune; Almarsdottir, Anna Birna; Hansen, Johanne M.; Titkov, Dmitry; Rachina, Svetlana; Panfilova, Ekaterina; Merkulova, Viktoria; Eseva, Olga; Riabkova, Nadezhda; Kaae, Susanne

A Qualitative Analysis of the Culture of Antibiotic Use for Upper Respiratory Tract Infections Among Patients in Northwest Russia

Akrong, Grace; Chauzy, Alexia; Aranzana-Climent, Vincent; Lacroix, Mathilde; Deroche, Luc; Prouvensier, Laure; Buyck, Julien M.; Couet, William; Marchand, Sandrine

A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro

Bondesson, Elisabeth; Joud, Anna; Stigmar, Kjerstin; Ringqvist, Asa; Kraepelien, Martin; Kaldo, Viktor; Wettermark, Björn; Forsell, Yvonne; Petersson, Ingemar F.; Schelin, Maria E. C.

Utilization of healthcare and prescription medicines after non-pharmacological interventions for depression - A 3-year register follow-up of an RCT in primary care

Johannesson, Jenny; Hansson, Paula; Bergström, Christel; Paulsson, Mattias

Manipulations and age-appropriateness of oral medications in pediatric oncology patients in Sweden: Need for personalized dosage forms

Brem, Jürgen; Panduwawala, Tharindi; Hansen, Jon Ulf; Hewitt, Joanne; Liepins, Edgars; Donets, Pawel; Espina, Laura; Farley, Alistair J M; Shubin, Kirill; Campillos, Gonzalo Gomez; Kiuru, Paula; Shishodia, Shifali; Krahn, Daniel; Leśniak, Robert K; Schmidt Adrian, Juliane; Calvopiña, Karina; Turrientes, María-Carmen; Kavanagh, Madeline E; Lubriks, Dmitrijs; Hinchliffe, Philip; Langley, Gareth W; Aboklaish, Ali F; Eneroth, Anders; Backlund, Maria; Baran, Andrei G; Nielsen, Elisabet I.; Speake, Michael; Kuka, Janis; Robinson, John; Grinberga, Solveiga; Robinson, Lindsay; McDonough, Michael A; Rydzik, Anna M; Leissing, Thomas M; Jimenez-Castellanos, Juan Carlos; Avison, Matthew B; Da Silva Pinto, Solange; Pannifer, Andrew D; Martjuga, Marina; Widlake, Emma; Priede, Martins; Hopkins Navratilova, Iva; Gniadkowski, Marek; Belfrage, Anna Karin; Brandt, Peter; Yli-Kauhaluoma, Jari; Bacque, Eric; Page, Malcolm G P; Björkling, Fredrik; Tyrrell, Jonathan M; Spencer, James; Lang, Pauline A; Baranczewski, Pawel; Cantón, Rafael; McElroy, Stuart P; Jones, Philip S; Baquero, Fernando; Suna, Edgars; Morrison, Angus; Walsh, Timothy R; Schofield, Christopher J

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

Hellinen, Laura; Koskela, Ali; Vattulainen, Elina; Liukkonen, Mikko; Wegler, Christine; Treyer, Andrea; Handin, Niklas; Svensson, Richard; Myohanen, Timo; Poso, Antti; Kaarniranta, Kai; Artursson, Per; Urtti, Arto

Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration

Hossain, Md Shakhawath; Parrow, Albin; Kabedev, Aleksei; Kneiszl, Rosita C.; Leng, Yuning; Larsson, Per

Explicit-pH Coarse-Grained Molecular Dynamics Simulations Enable Insights into Restructuring of Intestinal Colloidal Aggregates with Permeation Enhancers

Kneiszl, Rosita C.; Hossain, Md Shakhawath; Larsson, Per

In Silico-Based Experiments on Mechanistic Interactions between Several Intestinal Permeation Enhancers with a Lipid Bilayer Model

Havervall, Sebastian; Ng, Henry; Jernbom Falk, August; Greilert-Norin, Nina; Månberg, Anna; Marking, Ulrika; Laurén, Ida; Gabrielsson, Lena; Salomonsson, Ann-Christin; Aguilera, Katherina; Kihlgren, Martha; Månsson, Maja; Rosell, Axel; Hellström, Cecilia; Andersson, Eni; Olofsson, Jennie; Skoglund, Lovisa; Yousef, Jamil; Pin, Elisa; Lord, Martin; Åberg, Mikael; Hedhammar, My; Tegel, Hanna; Dönnes, Pierre; Phillipson, Mia; Nilsson, Peter; Klingström, Jonas; Mangsbo, Sara; Hober, Sophia; Thålin, Charlotte

Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19

Vertzoni, M; Alsenz, J; Augustijns, P; Bauer-Brandl, A; Bergström, Christel; Brouwers, J; Müllerz, A; Perlovich, G; Saal, C; Sugano, K; Reppas, C

UNGAP best practice for improving solubility data quality of orally administered drugs

Rosenlund Lau, Sofie; Kaae, Susanne; Kälvemark Sporrong, Sofia

Ethnography and its potential for studying the social in social pharmacy: An example of autonomy and pharmaceuticals in eldercare

Vertzoni, M.; Alsenz, J.; Augustijns, P.; Bauer-Brandl, A.; Bergström, Christel A. S.; Brouwers, J.; Mullerz, A.; Perlovich, G.; Saal, C.; Sugano, K.; Reppas, C.

UNGAP best practice for improving solubility data quality of orally administered drugs

Kälvemark Sporrong, Sofia; Kaae, S.; Nørgaard, L. S.; Møllebaek, M.; Waaseth, M.; Cantarero Arevalo, L.; Ljungberg Persson, C.; Bekker, C. L.; Falby Lindell, J.; Druedahl, L.

Challenges in qualitative social pharmacy research: Reflections based on a conference workshop

Swartling, Maria; Smekal, Anna-Karin; Furebring, Mia; Lipcsey, Miklós; Jönsson, Siv; Nielsen, Elisabet I.

Population pharmacokinetics of cefotaxime in intensive care patients

Komen, Joris; Pottegård, Anton; Hjemdahl, Paul; Mantel-Teeuwisse, Aukje K; Wettermark, Björn; Hellfritzsch, Maja; Hallas, J; Herings, Ron; Smits, Lisa; Forslund, Thomas; Klungel, Olaf

Non-vitamin K antagonist oral anticoagulants, proton pump inhibitors and gastrointestinal bleeds

Keemink, Janneke; Hedge, Oliver; Bianco, Valentina; Hubert, Madlen; Bergström, Christel

Comparison of cellular monolayers and an artificial membrane as absorptive membranes in the in vitro lipolysis-permeation assay

Zdovc, Jurij Aguiar; Hanzel, Jurij; Kurent, Tina; Sever, Nejc; Kozelj, Matic; Smrekar, Natasa; Novak, Gregor; Stabuc, Borut; Dreesen, Erwin; Thomas, Debby; Vovk, Tomaz; Ostanek, Barbara; Drobne, David; Grabnar, Iztok

Ustekinumab Dosing Individualization in Crohn's Disease Guided by a Population Pharmacokinetic-Pharmacodynamic Model

Sadiq, Muhammad Waqas; Holz, Olaf; Ellinghusen, Birthe D.; Faulenbach, Cornelia; Mueller, Meike; Badorrek, Philipp; Eriksson, Ulf G.; Fridén, Markus; Stomilovic, Stina; Lundqvist, Anders J.; Hohlfeld, Jens M.

Lung pharmacokinetics of inhaled and systemic drugs: A clinical evaluation

Kim, Seongho; Hooker, Andrew; Shi, Yu; Kim, Grace Hyun J.; Wong, Weng Kee

Metaheuristics for pharmacometrics

Ryeznik, Yevgen; Sverdlov, Oleksandr; Svensson, Elin; Montepiedra, Grace; Hooker, Andrew; Wong, Weng Kee

Pharmacometrics meets statistics-A synergy for modern drug development

De Winter, Sabrina; van Hest, Reinier; Dreesen, Erwin; Annaert, Pieter; Wauters, Joost; Meersseman, Wouter; Van den Eede, Nele; Desmet, Stefanie; Verelst, Sandra; Vanbrabant, Peter; Peetermans, Willy; Spriet, Isabel

Quantification and Explanation of the Variability of First-Dose Amikacin Concentrations in Critically Ill Patients Admitted to the Emergency Department: A Population Pharmacokinetic Analysis

Kantasiripitak, Wannee; Verstockt, Bram; Alsoud, Dahham; Lobaton, Triana; Thomas, Debby; Gils, Ann; Vermeire, Severine; Ferrante, Marc; Dreesen, Erwin

The effect of aging on infliximab exposure and response in patients with inflammatory bowel diseases

Bauer, Robert J.; Hooker, Andrew; Mentre, France

Tutorial for $DESIGN in NONMEM: Clinical trial evaluation and optimization

Svensson, Robin J.; Ribbing, Jakob; Kotani, Naoki; Dolton, Michael; Vadhavkar, Shweta; Cheung, Dorothy; Staton, Tracy; Choy, David F.; Putnam, Wendy; Jin, Jin; Budha, Nageshwar; Karlsson, Mats; Quartino, Angelica; Zhu, Rui

Population repeated time-to-event analysis of exacerbations in asthma patients: A novel approach for predicting asthma exacerbations based on biomarkers, spirometry, and diaries/questionnaires

Krishnan, Sreenath M.; Friberg, Lena E.; Bruno, René; Beyer, Ulrich; Jin, Jin Y.; Karlsson, Mats O.

Multistate model for pharmacometric analyses of overall survival in HER2-negative breast cancer patients treated with docetaxel

Ngwalero, Precious; Brust, James C. M.; van Beek, Stijn W.; Wasserman, Sean; Maartens, Gary; Meintjes, Graeme; Joubert, Anton; Norman, Jennifer; Castel, Sandra; Gandhi, Neel R.; Denti, Paolo; McIlleron, Helen; Svensson, Elin; Wiesner, Lubbe

Relationship between Plasma and Intracellular Concentrations of Bedaquiline and Its M2 Metabolite in South African Patients with Rifampin-Resistant Tuberculosis

Tanneau, Lénaïg; Svensson, Elin; Rossenu, Stefaan; Karlsson, Mats

Exposure–safety analysis of QTc interval and transaminase levels following bedaquiline administration in patients with drug‐resistant tuberculosis

Handin, Niklas; Mickols, Evgeniya; Ölander, Magnus; Rudfeldt, Jakob; Blom, Kristin; Nyberg, Frida; Senkowski, Wojciech; Urdzik, Jozef; Maturi, Varun; Fryknäs, Mårten; Artursson, Per

Conditions for maintenance of hepatocyte differentiation and function in 3D cultures

Wynendaele, Evelien; Furman, Christophe; Wielgomas, Bartosz; Larsson, Per; Hak, Eelko; Block, Thomas; Van Calenbergh, Serge; Willand, Nicolas; Markuszewski, Michal; Odell, Luke R.; Poelarends, Gerrit J.; De Spiegeleer, Bart

Sustainability in drug discovery

Grudén, Stefan; Forslund, Anders; Alderborn, Göran; Söderhäll, Arvid; Hellström, Per M.; Holmbäck, Ulf

Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose.

Elkayal, Omar; Allegaert, Karel; Spriet, Isabel; Smits, Anne; Seghaye, Marie-Christine; Charlier, Corinne; Dreesen, Erwin

Population pharmacokinetics of cefazolin in maternal and umbilical cord plasma, and simulated exposure in term neonates

Garcia-Prats, Anthony J.; Svensson, Elin; Winckler, Jana; Draper, Heather R.; Fairlie, Lee; van der Laan, Louvina E.; Masenya, Masebole; Schaaf, H. Simon; Wiesner, Lubbe; Norman, Jennifer; Aarnoutse, Rob E.; Karlsson, Mats O.; Denti, Paolo; Hesseling, Anneke C.

Pharmacokinetics and safety of high-dose rifampicin in children with TB: the Opti-Rif trial

Chao, Meie; Öblom, Heidi; Cornett, Claus; Bøtker, Johan; Rantanen, Jukka; Kälvemark Sporrong, Sofia; Genina, Natalja

Data-Enriched Edible Pharmaceuticals (DEEP) with Bespoke Design, Dose and Drug Release

van Boven, Job F. M.; Tsiligianni, Ioanna; Potocnjak, Ines; Mihajlovic, Jovan; Dima, Alexandra L.; Nabergoj Makovec, Urska; Ágh, Tamás; Kardas, Prezmyslaw; Ghiciuc, Cristina Mihaela; Petrova, Guenka; Bitterman, Noemi; Kamberi, Fatjona; Culig, Josip; Wettermark, Björn

European Network to Advance Best Practices and Technology on Medication Adherence: Mission Statement

Elkayal, Omar; Spriet, Isabel; Uyttebroeck, Anne; Colita, Anca; Annaert, Pieter; Allegaert, Karel; Smits, Anne; Van Daele, Ruth; Dreesen, Erwin

A Population Pharmacokinetic Modeling and Simulation Study of Posaconazole Oral Suspension in Immunocompromised Pediatric Patients: A Short Communication

Edueng, Khadijah; Kabedev, Aleksei; Ekdahl, Alyssa; Mahlin, Denny; Baumann, John; Mudie, Deanna; Bergström, Christel

Pharmaceutical Profiling and Molecular Dynamics Simulations Reveal Crystallization Effects in Amorphous Formulations

Flörkemeier, Inken; Steinhauer, Tamara N.; Hedemann, Nina; Ölander, Magnus; Artursson, Per; Clement, Bernd; Bauerschlag, Dirk O.

Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer

van Eerden, Ruben A. G.; van Doorn, Leni; de Man, Femke M.; Heersche, Niels; Doukas, Michail; van den Bosch, Thierry P. P.; Oomen-de Hoop, Esther; de Bruijn, Peter; Bins, Sander; Ibrahim, Eman; Nikkessen, Suzan; Friberg, Lena; Koolen, Stijn L. W.; Spaander, Manon C. W.; Mathijssen, Ron H. J.

Tissue Type Differences in ABCB1 Expression and Paclitaxel Tissue Pharmacokinetics in Patients With Esophageal Cancer