Publications

  • Asad, Shno; Wegler, Christine; Ahl, David; Bergström, Christel A. S. et al.

    Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease

    Part of Journal of Pharmaceutical Sciences, p. 239-250, 2021.

    DOI Uploaded full-text To DiVA

    Open access

  • Berg, Staffan; Krause, Julius; Björkbom, Anders; Walter, Katrin et al.

    In Vitro and In Vivo Evaluation of 3D Printed Capsules with Pressure Triggered Release Mechanism for Oral Peptide Delivery

    Part of Journal of Pharmaceutical Sciences, p. 228-238, 2021.

    DOI To DiVA

  • Kuentz, Martin; Bergström, Christel A.S.

    Synergistic Computational Modeling Approaches as Team Players in the Game of Solubility Predictions

    Part of Journal of Pharmaceutical Sciences, p. 22-34, 2021.

    DOI To DiVA

  • Matsson, Pär; Baranczewski, Pawel; Giacomini, Kathleen M.; Andersson, Tommy B. et al.

    A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research

    Part of Journal of Pharmaceutical Sciences, p. 2-11, 2021.

    DOI To DiVA

  • Kabedev, Aleksei; Hossain, Shakhawath; Hubert, Madlen; Larsson, Per et al.

    Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs: impact of bile solubilization and drug aggregation

    Part of Journal of Pharmaceutical Sciences, p. 176-185, 2021.

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    Open access

  • Wright, Leah; Joyce, Paul; Barnes, Timothy J.; Lundmark, Richard et al.

    A comparison of chitosan, mesoporous silica and poly(lactic-co-glycolic) acid nanocarriers for optimising intestinal uptake of oral protein therapeutics

    Part of Journal of Pharmaceutical Sciences, p. 217-227, 2021.

    DOI To DiVA

  • Wegler, Christine; Matsson, Pär; Krogstad, Veronica; Urdzik, Jozef et al.

    Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes

    Part of Molecular Pharmaceutics, p. 1792-1805, 2021.

    DOI To DiVA

  • Sou, Tomás; Bergström, Christel A. S.

    Contemporary formulation development for inhaled pharmaceuticals

    Part of Journal of Pharmaceutical Sciences, p. 66-86, 2021.

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    Open access

  • Wegler, Christine; Gazit, Meryem; Issa, Karolina; Subramaniam, Sujay et al.

    Expanding the Efflux In Vitro Assay Toolbox: A CRISPR-Cas9 Edited MDCK Cell Line with Human BCRP and Completely Lacking Canine MDR1

    Part of Journal of Pharmaceutical Sciences, p. 388-396, 2021.

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  • Johannesson, Jenny; Khan, Jamal; Hubert, Madlen; Teleki, Alexandra et al.

    3D-printing of solid lipid tablets from emulsion gels

    Part of International Journal of Pharmaceutics, 2021.

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  • Wegler, Christine; Ölander, Magnus; Lundquist, Patrik; Artursson, Per

    Global variability analysis of mRNA and protein concentrations across and within human tissues

    Part of NAR genomics and bioinformatics, 2020.

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    Open access

  • Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K. et al.

    A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity

    Part of Drug Metabolism And Disposition, p. 8-17, 2020.

    DOI To DiVA

  • Mudie, Deanna M.; Samiei, Nasim; Marshall, Derrick J.; Amidon, Gregory E. et al.

    Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties

    Part of AAPS Journal, 2020.

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    Open access

  • Rendo, Verónica; Stoimenov, Ivaylo; Mateus, André; Sjöberg, Elin et al.

    Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy

    Part of Nature Communications, 2020.

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    Open access

  • Sou, Tomás; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Friberg, Lena et al.

    Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

    Part of Molecular Pharmaceutics, p. 1458-1469, 2020.

    DOI To DiVA

  • Antonescu, Irina E.; Karlgren, Maria; Pedersen, Maria L.; Simoff, Ivailo et al.

    Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug-Drug Interactions

    Part of Pharmaceutics, 2020.

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    Open access

  • Soukarieh, Fadi; Liu, Ruiling; Romero, Manuel; Roberston, Shaun N. et al.

    Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

    Part of Frontiers in Chemistry, 2020.

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    Open access

  • Hedge, Oliver; Bergström, Christel A. S.

    Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations

    Part of Pharmaceutical research, 2020.

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    Open access

  • Teleki, Alexandra; Nylander, Olivia; Bergström, Christel

    Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media

    Part of Pharmaceutics, 2020.

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    Open access

  • Ölander, Magnus; Wisniewski, Jacek R.; Artursson, Per

    Cell-type-resolved proteomic analysis of the human liver

    Part of Liver international (Print), p. 1770-1780, 2020.

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    Open access

  • Larsson, Per; Kneiszl, Rosita C.; Marklund, Erik

    MkVsites: A tool for creating GROMACS virtual sites parameters to increase performance in all-atom molecular dynamics simulations.

    Part of Journal of Computational Chemistry, p. 1564-1569, 2020.

    DOI To DiVA

  • Bergström, Christel; Llinas, Antonio

    Strategies of solubility enhancement and perspectives in solubility measurements of pharmaceutical compounds

    Part of ADMET & DMPK, p. 176-179, 2020.

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    Open access

  • El Sayed, Mira; Alhalaweh, Amjad; Bergström, Christel A. S.

    Insights into Dissolution and Solution Chemistry of Multidrug Formulations of Antihypertensive Drugs

    Part of Molecular Pharmaceutics, p. 4018-4028, 2020.

    DOI To DiVA

  • Alvebratt, Caroline; Dening, Tahnee J; Åhlén, Michelle; Cheung, Ocean et al.

    In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier

    Part of Pharmaceutics, 2020.

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    Open access

  • Alvebratt, Caroline; Keemink, Janneke; Edueng, Khadijah; Cheung, Ocean et al.

    An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems

    Part of European journal of pharmaceutics and biopharmaceutics, p. 21-29, 2020.

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    Open access

  • Sou, Tomás; Soukarieh, Fadi; Williams, Paul; Stocks, Michael J. et al.

    Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions

    Part of ACS Omega, p. 25733-25746, 2020.

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    Open access

  • Hossain, Shakhawath; Joyce, Paul; Parrow, Albin; Jõemetsa, Silver et al.

    Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers

    Part of Molecular Pharmaceutics, p. 4226-4240, 2020.

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    Open access

  • Parrow, Albin; Larsson, Per; Augustijns, Patrick; Bergström, Christel A. S.

    Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids: Impact on Drug Solubilization

    Part of Molecular Pharmaceutics, p. 3837-3844, 2020.

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    Open access

  • Joyce, Paul; Jõemetsa, Silver; Isaksson, Simon; Hossain, Shakhawath et al.

    TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica

    Part of Angewandte Chemie International Edition, 2020.

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    Open access

  • Wegler, Christine; Prieto Garcia, Luna; Klinting, Signe; Robertsen, Ida et al.

    Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients with a Wide Range of Body Weight

    Part of Clinical Pharmacology and Therapeutics, 2020.

    DOI To DiVA

  • Artursson, Per; Lundquist, Patrik

    A new opening for orally taken peptide drugs

    Part of Nature Biomedical Engineering, p. 12-13, 2020.

    DOI To DiVA

  • Di, Li; Artursson, Per; Avdeef, Alex; Benet, Leslie Z et al.

    The Critical Role of Passive Permeability in Designing Successful Drugs

    Part of ChemMedChem, p. 1862-1874, 2020.

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    Open access

  • Sou, Tomás; Kukavica-Ibrulj, Irena; Soukarieh, Fadi; Halliday, Nigel et al.

    Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection

    Part of Journal of Pharmaceutical Sciences, p. 630-640, 2019.

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    Open access

  • Alhalaweh, Amjad; Alzghoul, Ahmad; Bergström, Christel A. S.

    Molecular Drivers of Crystallization Kinetics for Drugs in Supersaturated Aqueous Solutions

    Part of Journal of Pharmaceutical Sciences, p. 252-259, 2019.

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    Open access

  • Nies, A. T.; Handin, Niklas; Schaeffeler, E.; Haag, M. et al.

    Comprehensive drug uptake transporter proteomics and metabolomic profiling of human liver

    Part of Naunyn-Schmiedeberg's Archives of Pharmacology, p. S8-S8, 2019.

    DOI To DiVA

  • Amidon, Gregory E.; Anderson, Bradley D.; Balthasar, Joseph P.; Bergström, Christel A.S. et al.

    Fifty-Eight Years and Counting: High-Impact Publishing in Computational Pharmaceutical Sciences and Mechanism-Based Modeling

    Part of Journal of Pharmaceutical Sciences, p. 2-7, 2019.

    DOI To DiVA

  • Artursson, Per

    Experimental approaches to understand intracellular based drug bioavailability

    Part of Drug Metabolism and Pharmacokinetics, p. S3-S3, 2019.

    DOI To DiVA

  • Filppula, Anne M.; Parvizi, Rezvan; Mateus, André; Baranczewski, Pawel et al.

    Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

    Part of Scientific Reports, 2019.

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    Open access

  • Keemink, Janneke; Martensson, Elin; Bergström, Christel

    Lipolysis-Permeation Setup for Simultaneous Study of Digestion and Absorption in Vitro

    Part of Molecular Pharmaceutics, p. 921-930, 2019.

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    Open access

  • Ölander, Magnus; Wiśniewski, Jacek R.; Flörkemeier, Inken; Handin, Niklas et al.

    A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes

    Part of Archives of Toxicology, p. 819-829, 2019.

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    Open access

  • Bergström, Christel A.S.; Avdeef, Alex

    Perspectives in solubility measurement and interpretation

    Part of ADMET AND DMPK, p. 88 88-105 105, 2019.

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    Open access

  • Ölander, Magnus; Handin, Niklas; Artursson, Per

    Image-based quantification of cell debris as a measure of apoptosis

    Part of Analytical Chemistry, p. 5548-5552, 2019.

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    Open access

  • Bergström, Christel; Box, Karl; Holm, Rene; Matthews, Wayne et al.

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

    Part of European journal of pharmaceutics and biopharmaceutics, p. 101-114, 2019.

    DOI To DiVA

  • Wisniewski, Jacek R.; Wegler, Christine; Artursson, Per

    Multiple-Enzyme-Digestion Strategy Improves Accuracy and Sensitivity of Label- and Standard-Free Absolute Quantification to a Level That Is Achievable by Analysis with Stable Isotope-Labeled Standard Spiking

    Part of Journal of Proteome Research, p. 217-224, 2019.

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    Open access

  • Treyer, Andrea; Ullah, Mohammed; Parrott, Neil; Molitor, Birgit et al.

    Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies

    Part of AAPS Journal, 2019.

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    Open access

  • Charalabidis, Aggelos; Sfouni, Maria; Bergström, Christel; Macheras, Panos

    The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS): Beyond guidelines

    Part of International Journal of Pharmaceutics, p. 264-281, 2019.

    DOI To DiVA

  • Keemink, Janneke; Sjögren, Erik; Holm, Rene; Bergström, Christel A. S.

    Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?

    Part of Journal of Pharmaceutical Sciences, p. 1765-1771, 2019.

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    Open access

  • Boyd, Ben J.; Bergström, Christel; Vinarov, Zahari; Kuentz, Martin et al.

    Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

    Part of European Journal of Pharmaceutical Sciences, 2019.

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    Open access

  • Edueng, Khadijah; Mahlin, Denny; Gråsjö, Johan; Nylander, Olivia et al.

    Supersaturation Potential of Amorphous Active Pharmaceutical Ingredients after Long-Term Storage

    Part of Molecules, 2019.

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    Open access

  • Alvebratt, Caroline; Denning, T.; Prestidge, Cliff; Bergström, Christel et al.

    Advanced methodologies to study in vitro digestion of a lipid-loaded mesoporous drug carrier

    Part of Preclinical Form and Formulation for Drug Discovery, Gordon Research Conference 2019, 2019.

    To DiVA

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